Zvinowanzoitika zvinosanganisira kusvotwa uye kuputika [4], uye zvinogonawo kuwedzera njodzi ye candidiasis; Kana yakasanganiswa ne clavulanic acid (inoti amoxicillin clavulanic acid potassium), pachave nemhedzisiro yemanyoka [5]. Usashandise zvinodhaka kune vanhu vane allergic kune penicillin; Varwere vane renal kukundikana vanogona kutora chigadzirwa ichi, asi dose inofanira kuderedzwa. Kutora mushonga panguva yekuzvitakura uye kuyamwisa hakuratidzi kukuvadza parizvino [4].

Amoxicillin yakanyorwa muna 1972 [6]. Mushonga uyu wakanyorwa muWorld Health Organisation's list yemishonga yakakosha, inova imwe yemishonga yakakosha muhurongwa hwekurapa [7] uye mushonga unorwisa mabhakitiriya unonyanya kushandiswa kuvana [8]. Amoxicillin ndeyemushonga wesainzi [4]. Mutengo wehorese wemushonga wega wega uri pakati pe0.02 ne0.05 USD [9]. MuUnited States, kosi yemazuva gumi yekurapwa inoita madhora gumi nematanhatu [4].

Amoxicillin BP

Amoxicillin 250 mg capsules

chiito musimboti

Amoxicillin inoshanda nekudzivisa kuumbwa kwebhakitiriya sero madziro. Iyo inodzivisa kubatana pakati pemutsara peptidoglycan polymer cheni izvo zvinonyanya zvikamu zvesero madziro eGram-positive bacteria uye Gram-negative mabhakitiriya.

zvinokuvadza

Zvikonzero zvinosanganisira kuda kurutsa, kurutsa, kushatirwa uye antibiotic colitis, uye manyoka anogonawo kuitika. Muzviitiko zvisingawanzoitiki, zvinyorwa zvezvokurapa zvinoratidza kuti migumisiro yechirwere inosanganisira kuchinja kwepfungwa, dzungu, kuvhiringidzika mupfungwa, kuzvidya mwoyo, uye paranoia (kunzwa kuchiedza, inzwi, uye pfungwa dzisina kujeka).

anaphylactic reaction

Alergic reaction inokonzerwa neamoxicillin inogona kutarisirwa isingatarisirwi uye yakaoma, uye kurapwa kunofanirwa kutsvakwa nekukurumidza sezvinobvira. Kuita kwerudzi urwu kunowanzotanga nekushanduka kwepfungwa panguva yekutanga, kuchiteverwa nekukwenya kweganda kunoperekedzwa nekukwenya kwakasimba (kazhinji kunotanga kubva pamunwe uye kumativi ezvidya uye kupararira nekukurumidza), kunzwa kupisa, kusvotwa uye kurutsa. Chero zvimwe zviratidzo zvisingambofungidziri zvinofanira kubatwa zvakanyanya.

Amoxicillin kwete allergic ganda rash.

3-10% yevana vanotora amoxicillin (kana ampicillin) uye vanoita mapundu (72 maawa mushure mekutora penicillin), asi zvinogona kuitikawo kuvanhu vakuru. Dzimwe nguva inonzi "amoxicillin rash".

Rash inotsanangurwa semaculopapular rash kana gwirikwiti (yakafanana negwirikwiti), saka inonzi "gwirikwiti-kunge mapundu anokonzerwa neamoxicillin" mumabhuku ekurapa. Inotanga muhunde uye inopararira kubva ipapo. Haisi chaiyo allergic reaction, uye hapana chikonzero chekumisa chirongwa chekurapa chazvino. Nekudaro, iyi yakajairwa amoxicillin rash uye ine njodzi yeallergic reaction kazhinji haisi nyore kusiyanisa.

Non-allergic amoxicillin rash inogonawo kuva chiratidzo chetapukira mononucleosis. Zvimwe zvidzidzo zvinoratidza kuti chikamu che80-90% chevarwere vanozoita rash iyi kana vabatwa nehutachiona hweEB uye kurapwa neamoxicillin kana ampicillin.