English
Amoxicillin [1] [2] (Inn: amoxicillin), also translated as amoxicillin or amoxicillin, whose real name is amoxicillin [3], is a commonly used oral broad-spectrum β -lactam antibiotic, which has bacteriolytic effect and is mainly used to treat bacterial infections caused by susceptible microorganisms [4]. This product is the first-line medication for otitis media, and can also be used to treat symptoms such as streptococcal pharyngitis, pneumonia, cellulitis and urinary tract infection [4]. Combined with clavulanic acid, the drug resistance of bacteria can be effectively weakened.
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Common side effects include nausea and rash [4], and may also increase the risk of candidiasis; If combined with clavulanic acid (namely amoxicillin clavulanic acid potassium), there will be side effects of diarrhea [5]. Do not use drugs for people who are allergic to penicillin; Patients with renal failure can take this product, but the dose must be reduced. Taking medicine during pregnancy and lactation shows no harm at present [4].
Amoxicillin was listed in 1972 [6]. This drug is listed in the World Health Organization's list of essential drugs, which is one of the essential drugs in the medical system [7] and the most commonly used antibiotic for children [8]. Amoxicillin belongs to the scientific drug [4]. The wholesale price of each medicine is between 0.02 and 0.05 USD [9]. In the United States, a ten-day course of treatment costs about $16 [4].
Amoxicillin BP
Amoxicillin 250 mg capsules
action principle
Amoxicillin works by inhibiting the synthesis of bacterial cell walls. It inhibits the linkage between linear peptidoglycan polymer chains which are the main components of the cell walls of Gram-positive bacteria and Gram-negative bacteria.
harmful effect
Side effects include nausea, vomiting, irritability and antibiotic colitis, and diarrhea may also occur. In rare cases, medical records show that side effects include mental changes, dizziness, mental confusion, anxiety, and paranoia (sensitivity to light, sound, and unclear thoughts).
anaphylactic reaction
The allergic reaction caused by amoxicillin can be expect the unexpected and severe, and medical treatment must be sought as soon as possible. This kind of reaction often begins with mental changes at the initial stage, followed by skin rash accompanied by strong itching (usually starting from fingertips and around groin and spreading rapidly), burning sensation, nausea and vomiting. Any other symptoms that don't even seem suspicious must be dealt with seriously.
Amoxicillin not allergic skin rash.
3-10% of children take amoxicillin (or ampicillin) and get a rash (72 hours after taking penicillin), but it may also happen to adults. It is sometimes called "amoxicillin rash".
Rash is described as maculopapular rash or measles (measles-like), so it is called "measles-like rash induced by amoxicillin" in medical literature. It starts in the trunk and spreads from there. It is not a real allergic reaction, and there is no need to stop the current treatment plan. However, this common amoxicillin rash and dangerous allergic reaction are usually not easy to distinguish.
Non-allergic amoxicillin rash may also be an indicator of infectious mononucleosis. Some studies show that about 80-90% patients will develop this rash when they are infected with acute EB virus and treated with amoxicillin or ampicillin.
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