Miao
Amoxicillin [1] [2] (Inn: amoxicillin), kuj txhais tau tias yog amoxicillin lossis amoxicillin, uas nws lub npe tiag tiag yog amoxicillin [3], yog ib qho siv ntau qhov ncauj broad-spectrum β-lactam tshuaj tua kab mob, uas muaj cov kab mob bacteriolytic thiab feem ntau yog siv. kho cov kab mob uas tshwm sim los ntawm cov kab mob uas raug kab mob [4]. Cov khoom no yog thawj kab tshuaj rau otitis media, thiab tseem tuaj yeem siv los kho cov tsos mob xws li streptococcal pharyngitis, mob ntsws, cellulitis thiab kab mob urinary [4]. Ua ke nrog clavulanic acid, cov tshuaj tiv thaiv kab mob tuaj yeem ua rau tsis muaj zog.
Khoom Paub meej
Cov kev mob tshwm sim feem ntau suav nrog xeev siab thiab pob liab liab [4], thiab tseem tuaj yeem ua rau muaj kev pheej hmoo ntawm candidiasis; Yog tias ua ke nrog clavulanic acid (xws li amoxicillin clavulanic acid poov tshuaj), yuav muaj kev phiv los ntawm raws plab [5]. Tsis txhob siv tshuaj rau cov neeg uas tsis haum rau penicillin; Cov neeg mob lub raum tsis ua haujlwm tuaj yeem noj cov khoom no, tab sis cov koob tshuaj yuav tsum raug txo. Noj tshuaj thaum cev xeeb tub thiab lactation qhia tsis muaj kev phom sij tam sim no [4].
Amoxicillin tau teev tseg hauv xyoo 1972 [6]. Cov tshuaj no tau teev tseg hauv World Health Organization cov npe tshuaj tseem ceeb, uas yog ib qho ntawm cov tshuaj tseem ceeb hauv kev kho mob [7] thiab feem ntau siv tshuaj tua kab mob rau cov menyuam yaus [8]. Amoxicillin belongs rau cov tshuaj scientific [4]. Tus nqi lag luam wholesale ntawm txhua cov tshuaj yog nyob nruab nrab ntawm 0.02 thiab 0.05 USD [9]. Hauv Tebchaws Meskas, kev kho mob kaum-hnub raug nqi txog $ 16 [4].
Amoxicillin BP
Amoxicillin 250 mg ntsiav tshuaj
txoj cai ua
Amoxicillin ua haujlwm los ntawm inhibiting cov synthesis ntawm cov phab ntsa ntawm cov kab mob. Nws inhibits kev sib txuas ntawm linear peptidoglycan polymer chains uas yog cov khoom tseem ceeb ntawm cov phab ntsa ntawm tes ntawm cov kab mob Gram-positive thiab Gram-negative bacteria.
phom sij
Cov kev mob tshwm sim muaj xws li xeev siab, ntuav, khaus khaus thiab tshuaj tua kab mob colitis, thiab raws plab kuj tuaj yeem tshwm sim. Muaj tsawg zaus, cov ntaub ntawv kho mob qhia tau hais tias cov kev mob tshwm sim muaj xws li kev hloov pauv ntawm lub hlwb, kiv taub hau, kev xav tsis meej pem, kev ntxhov siab, thiab paranoia (rhiab heev rau lub teeb, suab, thiab kev xav tsis meej).
anaphylactic tshuaj tiv thaiv
Cov tshuaj tsis haum los ntawm amoxicillin tuaj yeem ua rau qhov kev npaj txhij txog thiab hnyav, thiab kev kho mob yuav tsum tau nrhiav kom sai li sai tau. Cov tshuaj tiv thaiv no feem ntau pib nrog kev puas siab puas ntsws nyob rau hauv thawj theem, ua raws li daim tawv nqaij ua pob khaus nrog khaus khaus (feem ntau pib los ntawm cov ntiv tes thiab ib ncig ntawm puab tais thiab kis tau sai), kub hnyiab, xeev siab thiab ntuav. Lwm cov tsos mob uas tsis zoo li qhov tsis txaus ntseeg yuav tsum tau ua tiag tiag.
Amoxicillin tsis ua xua rau ntawm daim tawv nqaij.
3-10% ntawm cov menyuam yaus noj amoxicillin (los yog ampicillin) thiab tau pob liab liab (72 teev tom qab noj penicillin), tab sis nws kuj yuav tshwm sim rau cov neeg laus. Qee zaum nws yog hu ua "amoxicillin rash".
Rash yog piav raws li maculopapular pob los yog qhua pias (xws li qhua pias), yog li nws yog hu ua "measles-like rash induced by amoxicillin" nyob rau hauv cov ntaub ntawv kho mob. Nws pib hauv lub cev thiab kis los ntawm qhov ntawd. Nws tsis yog ib qho kev ua xua tiag tiag, thiab tsis tas yuav tsum tso tseg txoj kev npaj kho mob tam sim no. Txawm li cas los xij, qhov tshwm sim ntawm amoxicillin ua pob liab liab thiab qhov ua xua txaus ntshai no feem ntau tsis yooj yim kom paub qhov txawv.
Cov pob liab liab uas tsis ua rau amoxicillin tuaj yeem yog qhov qhia txog kev kis kab mob mononucleosis. Qee qhov kev tshawb fawb pom tau tias kwv yees li 80-90% cov neeg mob yuav tsim pob pob no thaum lawv kis tus kab mob EB mob hnyav thiab kho nrog amoxicillin lossis ampicillin.
Yam khoom
Nyob rau hauv 1985, Datong Locomotive Works pom tau hais tias hluav taws xob locomotives yog qhov tseem ceeb txoj kev loj hlob ntawm Tuam Tshoj railway locomotive thiab dov Tshuag lag luam nyob rau hauv lub neej yav tom ntej, thiab muab tso rau pem hauv ntej lub tswv yim tsim khoom ntawm "Nanzhu (Zhuzhou Electric Locomotive Works) thiab Datong Locomotive Works".
Shaoshan Hom 3 hluav taws xob locomotive yog kuv lub teb chaws thib ob tiam 6-axle neeg nrog caij thiab tsheb thauj mus los. Lub locomotive txais tus choj-hom tag nrho-yoj rectification thiab paub txog thyristor theem-tswj tus voltage tswj. Lub locomotive txais ib-theem AC 25kV 50Hz voltage system thiab muaj kev khiav hauj lwm siab tshaj plaws ntawm 100km / h.
Lub SS3B tsau hnyav hluav taws xob locomotive yog 12-axle freight electric locomotive. Nws muaj ob qhov zoo tib yam 6-qag locomotives txuas los ntawm ib lub coupler thiab ib lub tshuab cua. Ob ntu yog nruab nrog cov khoom siv hluav taws xob high-voltage connectors, tswj cables, thiab kev tiv thaiv network. Kab thiab cua system tswj ducts. Tag nrho lub tsheb tuaj yeem tswj tau synchronously ntawm txhua lub cab. Lub locomotive txais ib-theem fais fab zaus system, voltage 25kV, AC-DC kis tau tus mob, thiab lub siab tshaj plaws kev khiav hauj lwm ceev ntawm lub locomotive yog 100km / h.
Shaoshan 4 txhim kho hluav taws xob locomotive yog 8-axle freight locomotive. Lub locomotive muaj ob zoo tib yam plaub-axle locomotives txuas nrog ib tug coupler thiab ib tug windshield. Ob lub rooj cob qhia yog nruab nrog high-voltage connectors rau cov hluav taws xob system, reconnection tswj cables thiab cua nres system tswj ducts. Tag nrho lub tsheb tuaj yeem synchronously tswj los ntawm tus tsav tsheb cab ntawm ib qho ntawm lub tsheb. Ob lub locomotives tseem tuaj yeem sib cais thiab siv nws tus kheej ua plaub-qag locomotive.